HSV-TK substrate

CAT: 0804-HY-126218Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-126218Size:1 Each
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Description
HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity[1].
CAS Number
[111687-37-7]
UNSPSC
12352005
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsv-tk-substrate.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(N)=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)C3
Molecular Formula
C11H15N5O4
Molecular Weight
281.27
References & Citations
[1]Shewach DS, et al. Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells. Hum Gene Ther. 2002 Mar 1;13 (4) :543-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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