HSV-TK substrate

HSV-TK substrate

• CAS Number: 111687-37-7
• UNSPSC Description: HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity[1].
• Target Antigen: HSV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hsv-tk-substrate.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(N)=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)C3
• Molecular Weight: 281.27
• References & Citations: [1]Shewach DS, et al. Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells. Hum Gene Ther. 2002 Mar 1;13(4):543-51.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported