S1PR1 modulator 1

CAT: 0804-HY-126145-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-126145-01Size:1 mg
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Description
S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4[1].
CAS Number
[2328109-05-1]
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s1pr1-modulator-1.html
Purity
99.52
Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming)
Smiles
CC1=CC=CC=C1N2C(/C(S/C2=N\CCC)=C/C3=CC=C(OC(C)=O)C(C)=C3)=O
Molecular Formula
C23H24N2O3S
Molecular Weight
408.51
References & Citations
[1]Bell M, et al. Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1) . ACS Med Chem Lett. 2019 Feb 14;10 (3) :341-347.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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