KY-04031

• UNSPSC Description:

  KY-04031 is a potent PAK4 inhibitor with IC50 of 0.79 μM. KY-04031 binds to the ATP-binding pocket of PAK4. KY-04031 blocks tumor cell growth and invasion[1].

• Target Antigen:

  PAK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ky-04031.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=NC(NC2=CC3=C(NN=C3)C=C2)=NC(NCCC4=CNC5=C4C=CC=C5)=N1

• Molecular Weight:

  400.44

• References & Citations:

  [1]Byung Jun Ryu, et al. Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor. Cancer Lett. 2014 Jul 10;349(1):45-50.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  468056-29-3