KY-04045

• Description:

  KY-04045 is a PAK4 specific inhibitor (IC50=8.7 μM) that can be used for the development of anticancer drugs targeting PAK4[1].

• UNSPSC:

  12352005

• Target:

  PAK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ky-04045.html

• Smiles:

  CC (C1=NN (C) C=C1C2=NC3=CC (Br) =CN=C3N2) C

• Molecular Formula:

  C13H14BrN5

• Molecular Weight:

  320.19

• References & Citations:

  [1]Park, et al. "The discovery and the structural basis of an imidazo [4, 5-b] pyridine-based p21-activated kinase 4 inhibitor." Bioorganic & medicinal chemistry letters 26.11 (2016) : 2580-2583.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PAK4

• CAS Number:

  1223284-75-0