KY-04045

• Description :

  KY-04045 is a PAK4 specific inhibitor (IC50=8.7 μM) that can be used for the development of anticancer drugs targeting PAK4[1].

• UNSPSC :

  12352005

• Target :

  PAK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ky-04045.html

• Smiles :

  CC(C1=NN(C)C=C1C2=NC3=CC(Br)=CN=C3N2)C

• Molecular Formula :

  C13H14BrN5

• Molecular Weight :

  320.19

• References & Citations :

  [1]Park, et al. "The discovery and the structural basis of an imidazo [4, 5-b] pyridine-based p21-activated kinase 4 inhibitor." Bioorganic & medicinal chemistry letters 26.11 (2016) : 2580-2583.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PAK4

• CAS Number :

  [1223284-75-0]