R-96544 (free base)

R-96544 (free base)

• CAS Number: 167144-79-8
• UNSPSC Description: R-96544 (free base) is a potent, selective and competitive 5-HT2 receptor antagonist. R-96544 (free base) inhibits platelet aggregation induced by serotonin, and inhibits 5-HT2A receptor-mediated contraction of guinea pig trachea[1].
• Target Antigen: 5-HT Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/r-96544-free-base.html
• Solubility: 10 mM in DMSO
• Smiles: CN(C[C@@H](C1)O)[C@@H]1CCOC2=C(C=CC=C2)CCC3=CC(OC)=CC=C3
• Molecular Weight: 355.47
• References & Citations: [1]Ogawa T,et al. Pharmacological profiles of R-96544, the active form of a novel 5-HT2A receptor antagonist R-102444. Eur J Pharmacol. 2002;457(2-3):107-114. doi:10.1016/s0014-2999(02)02654-7
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported