Ro26-4550

• Description:

  Ro26-4550 is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM[1].

• UNSPSC:

  12352005

• Target:

  Interleukin Related

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ro26-4550.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC)[C@H](CC1=CC=C(C#CC2=CC=CC=C2)C=C1)NC(C[C@@H]3CN(C(N)=N)CCC3)=O

• Molecular Formula:

  C26H30N4O3

• Molecular Weight:

  446.54

• References & Citations:

  [1]Braisted AC, et al. Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J Am Chem Soc. 2003 Apr 2;125 (13) :3714-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [193744-04-6]