Ro26-4550

• Description :

  Ro26-4550 is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM[1].

• UNSPSC :

  12352005

• Target :

  Interleukin Related

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ro26-4550.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC)[C@H](CC1=CC=C(C#CC2=CC=CC=C2)C=C1)NC(C[C@@H]3CN(C(N)=N)CCC3)=O

• Molecular Formula :

  C26H30N4O3

• Molecular Weight :

  446.54

• References & Citations :

  [1]Braisted AC, et al. Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J Am Chem Soc. 2003 Apr 2;125 (13) :3714-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [193744-04-6]