SLV-317

• Description:

  SLV-317 is an antagonist of the neurokinin-1 receptor with oral activity. SLV-317 can effective antagonist of substance P-induced effects[1].

• UNSPSC:

  12352005

• Target:

  Neurokinin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/slv-317.html

• Smiles:

  O=C (C1=CC (C (F) (F) F) =CC (C (F) (F) F) =C1) N2[C@H] (CC3=CNC4=C3C=CC=C4) CN (CC5=NNN=C5CN6CCOCC6) CC2.Cl.Cl

• Molecular Formula:

  C30H33Cl2F6N7O2

• Molecular Weight:

  708.53

• References & Citations:

  [1]Christiane Hesse, et al. Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals. Br J Clin Pharmacol. 2006 Apr;61 (4) :414-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  393183-40-9