SLV-317

• Description :

  SLV-317 is an antagonist of the neurokinin-1 receptor with oral activity. SLV-317 can effective antagonist of substance P-induced effects[1].

• UNSPSC :

  12352005

• Target :

  Neurokinin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/slv-317.html

• Smiles :

  O=C(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N2[C@H](CC3=CNC4=C3C=CC=C4)CN(CC5=NNN=C5CN6CCOCC6)CC2.Cl.Cl

• Molecular Formula :

  C30H33Cl2F6N7O2

• Molecular Weight :

  708.53

• References & Citations :

  [1]Christiane Hesse, et al. Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals. Br J Clin Pharmacol. 2006 Apr;61 (4) :414-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [393183-40-9]