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GSK-2250665A

CAT: 0804-HY-120559-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-120559-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK-2250665A (Compound 13) is a selective Itk inhibitor with a pKi of 9.2.
CAS Number
1246030-96-5
UNSPSC
12352005
Target
Itk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gsk-2250665a.html
Purity
96.35
Solubility
10 mM in DMSO
Smiles
CCC1=CC=C2C(SC(NC3=NC(N[C@H]4CC[C@@H](CC4)O)=NC(CC5=CC=CC=C5)=C3)=N2)=C1
Molecular Formula
C26H29N5OS
Molecular Weight
459.61
References & Citations
[1]Alder CM, et al. Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy. ACS Med Chem Lett. 2013 Aug 12;4 (10) :948-52.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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