GSK-4716

• UNSPSC Description:

  GSK-4716 is a selective ERRβ/γ agonist.

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/GSK-4716.html

• Purity:

  99.82

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(N/N=C/C1=CC=C(C(C)C)C=C1)C2=CC=C(O)C=C2

• Molecular Weight:

  282.34

• References & Citations:

  [1]Wang SC, et al. An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells. Mol Cell Endocrinol. 2010 Feb 5;315(1-2):146-52.|[2]Rangwala SM, et al. Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity. J Biol Chem. 2010 Jul 16;285(29):22619-29.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  101574-65-6