UMB-32
CAT:
804-HY-117997
Size:
1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
UMB-32
- CAS Number: 1635437-39-6
- UNSPSC Description: UMB-32, a potent, selective BRD4 inhibitor, binds BRD4 with the Kd of 550 nM, and IC50 of 637 nM. UMB-32 also shows potency against TAF1, a bromodomain-containing transcription factor[1].
- Target Antigen: Epigenetic Reader Domain
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/umb-32.html
- Solubility: 10 mM in DMSO
- Smiles: CC(C)(NC1=C(C2=CC=C(C=C2)C3=C(ON=C3C)C)N=C4N1C=CN=C4)C
- Molecular Weight: 361.44
- References & Citations: [1]Michael R McKeown, et al. Biased multicomponent reactions to develop novel bromodomain inhibitors. J Med Chem. 2014 Nov 13;57(21):9019-27.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported