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HDAC-IN-9

CAT: 0804-HY-115941Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115941Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC-IN-9 is a potent and selective tubulin and HDAC dual inhibitor. HDAC-IN-9 inhibits the invasion and migration of A549 cells. HDAC-IN-9 shows potent antitumor and antiangiogenic effect in vitro and in vivo[1].
UNSPSC
12352005
Target
Apoptosis; HDAC; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-9.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12CC[C@@]3([C@H](CC[C@]3([C@@]1(CCC4=CC(OCC5=CC=C(C=C5)C(NC6=C(C=CC=C6)N)=O)=C(C=C42)OC)[H])[H])O)C
Molecular Formula
C33H38N2O4
Molecular Weight
526.67
References & Citations
[1]Sun M, et al. 2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response. Bioorg Chem. 2022; 120:105625.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2; HDAC6; HDAC8

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