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(S) -BAY-293

CAT: 0804-HY-114398ASize: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114398ASize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -BAY-293 is a negative control of BAY 293. BAY 293 is a potent KRAS-SOS1 interaction inhibitor[1].
CAS Number
2244904-69-4
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-bay-293.html
Solubility
10 mM in DMSO
Smiles
COC1=C(OC)C=C(N=C(C)N=C2N[C@@H](C)C3=CC(C4=C(CNC)C=CC=C4)=CS3)C2=C1
Molecular Formula
C25H28N4O2S
Molecular Weight
448.58
References & Citations
[1]Hillig RC, et, al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116 (7) :2551-2560.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported