CLK1/2-IN-2

CLK1/2-IN-2

• CAS Number: 1005776-20-4
• UNSPSC Description: CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 1.1 nM and 2.4 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/clk1-2-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CN2C(C=CC(C3=CNN=C3)=C2)=N1)C4=CC=C(N=C4)C(C)(C)C
• Molecular Weight: 360.41
• References & Citations: [1]Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported