CLK1/2-IN-2

• UNSPSC Description:

  CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 1.1 nM and 2.4 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/clk1-2-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CN2C(C=CC(C3=CNN=C3)=C2)=N1)C4=CC=C(N=C4)C(C)(C)C

• Molecular Weight:

  360.41

• References & Citations:

  [1]Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1005776-20-4