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CLK1/2-IN-2

CAT: 0804-HY-113670-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113670-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 1.1 nM and 2.4 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].
CAS Number
1005776-20-4
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clk1-2-in-2.html
Concentration
10mM
Purity
99.31
Solubility
DMSO : 35 mg/mL (ultrasonic)
Smiles
O=C(NC1=CN2C(C=CC(C3=CNN=C3)=C2)=N1)C4=CC=C(N=C4)C(C)(C)C
Molecular Formula
C20H20N6O
Molecular Weight
360.41
References & Citations
[1]Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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