CLK1/2-IN-1

CLK1/2-IN-1

• CAS Number: 1005784-23-5
• UNSPSC Description: CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 16 nM and 45 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/clk1-2-in-1.html
• Purity: 99.87
• Solubility: DMSO : ≥ 200 mg/mL
• Smiles: O=C(NC1=CN2C=C(C(F)(F)F)C=CC2=N1)C3=CC=C(C(C)(C)CCC4=NNN=N4)C=C3
• Molecular Weight: 443.43
• References & Citations: [1]Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported