Uridine 5'-diphosphate

Uridine 5'-diphosphate

• CAS Number: 58-98-0
• UNSPSC Description: Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor[1].
• Target Antigen: Endogenous Metabolite; P2Y Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/uridine-5-diphosphate.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O[C@H]1N2C(NC(C=C2)=O)=O
• Molecular Weight: 404.16
• References & Citations: [1]Ashleigh S Paparella, et al. Clostridioides difficile TcdB Toxin Glucosylates Rho GTPase by an SNi Mechanism and Ion Pair Transition State. ACS Chem Biol. 2022 Sep 16;17(9):2507-2518. |[2]Besada P, et al. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J Med Chem. 2006 Sep 7;49(18):5532-43.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported