Uridine diphosphate glucuronic acid (ammonium)

Uridine diphosphate glucuronic acid (ammonium)

• Alternative Name: UDP-α-D-glucuronic acid (ammonium)
• CAS Number: 43195-60-4
• UNSPSC Description: Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1].
• Target Antigen: Endogenous Metabolite
• Type: Biochemical Assay Reagents
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/uridine-diphosphate-glucuronic-acid-ammonium.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@@H](C(O)=O)O[C@H](OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)(O)=O)(O)=O)[C@H](O)[C@H]1O.[x].N
• References & Citations: [1]Annika J E Borg, et al. Mechanistic characterization of UDP-glucuronic acid 4-epimerase. FEBS J. 2021 Feb;288(4):1163-1178. |[2]DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported