5-(Trifluoromethyl)uridine

5-(Trifluoromethyl)uridine

• CAS Number: 21618-67-7
• UNSPSC Description: 5-(Trifluoromethyl)uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/5-trifluoromethyl-uridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=C(C(N1)=O)C(F)(F)F
• Molecular Weight: 312.20
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported