Uridine 5'-monophosphate

• UNSPSC Description:

  Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea[1][2][3].

• Target Antigen:

  Apoptosis; Cholinesterase (ChE); Endogenous Metabolite; Potassium Channel

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/Uridine_monophosphate.html

• Purity:

  99.89

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)|H2O : 150 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(O)=O

• Molecular Weight:

  324.18

• References & Citations:

  [1]Li G, et al. Uridine/UMP metabolism and their function on the gut in segregated early weaned piglets. Food Funct. 2019 Jul 17;10(7):4081-4089.|[2]Mehmet Cansev, et al. Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils. Brain Res. 2005 Oct 5;1058(1-2):101-8.|[3]Irina B Krylova, et al. The cardioprotective effect of uridine and uridine-5'-monophosphate: the role of the mitochondrial ATP-dependent potassium channel. Exp Gerontol. 2006 Jul;41(7):697-703.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  58-97-9