NCD38 (TFA)

CAT: 0804-HY-112304Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-112304Size:1 Each

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Description

NCD38 TFA is a LSD1-selective inhibitor[1][2].

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ncd38-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C(NCC3=CC=CC(Cl)=C3)=O)CCCCN[C@H]4[C@H](C5=CC=CC=C5)C4.O=C(O)C(F)(F)F

Molecular Formula

C37H37ClF3N3O4

Molecular Weight

680.16

References & Citations

[1]G R Sareddy, et al. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017 Apr 27;36 (17) :2423-2434.|[2]Yosuke Ota , et al. Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors. Bioorg Med Chem. 2018 Feb 1;26 (3) :775-785.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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