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ERK2 IN-1

CAT: 0804-HY-112300Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112300Size:1 Each
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Description
ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].
CAS Number
1093061-47-2
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ERK2_IN-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C2=NNC3=C2C=C(NC([C@@]4(SC)CN(CC(N5CCC(C6=CC=C(C7=NC=CC=N7)C=C6)=CC5)=O)CC4)=O)C=C3)C=C1
Molecular Formula
C36H34FN7O2S
Molecular Weight
647.76
References & Citations
[1]Boga SB, Discovery of 3 (S) -thiomethyl pyrrolidine ERK inhibitors for oncology. Bioorg Med Chem Lett. 2018 Jun 15;28 (11) :2029-2034.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK2

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