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ERK2/p38α MAPK-IN-1

CAT: 0931-T86382-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86382-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1016427-72-7
Target
P38 MAPK, ERK
Related Pathways
MAPK
Bioactivity
ERK2/p38α MAPK-IN-1 (Compound 1, In silico Hit-2), a selective inhibitor of ERK2 and p38α MAPK, exhibits potent activity with an IC 50 of 82 μM against ERK2. It uniquely binds to the allosteric sites of both ERK2 and p38α MAPK. This compound is utilized for type 2 diabetes research [1].
Smiles
O(C)C=1C=C2C(=CC1OC)SC(NC(=O)C=3N=C(COC4=CC=C(F)C=C4)SC3)=N2
Molecular Formula
C20H16FN3O4S2
Molecular Weight
445.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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