ERK2-IN-4

• UNSPSC Description:

  ERK2-IN-4 (Compound 6o) is an effective and selective ERK2 inhibitor with a Ki of 0.006 μM. ERK2-IN-4 inhibits the ERK signaling pathway and can be used in cancer research[1].

• Target Antigen:

  ERK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/erk2-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC(C1=CC=C(C(Cl)=C1)F)NC(C2=CC(C(NN=C3)=C3C4=CC(Cl)=CC=C4)=CN2)=O

• Molecular Weight:

  459.30

• References & Citations:

  [1]Aronov, Alex M et al. “Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.” Journal of medicinal chemistry vol. 50,6 (2007): 1280-7.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  933786-58-4