BzNH-BS

• UNSPSC Description:

  BzNH-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase[1].

• Target Antigen:

  SNIPERs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bznh-bs.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N[C@@H]([C@@H](C(N[C@@H](CC(C)C)C(NCCOCCOCCOCCOCCOCCNC(C1=CC=CC=C1)=O)=O)=O)O)CC2=CC=CC=C2

• Molecular Weight:

  674.82

• References & Citations:

  [1]Ohoka N, et al. SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib. Cancer Sci. 2017 May;108(5):1032-1041.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2443928-42-3