SQ 29548

• Description:

  SQ 29548 is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].

• UNSPSC:

  12352005

• Target:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/sq-29548.html

• Purity:

  99.9

• Solubility:

  DMSO : 5 mg/mL (ultrasonic; warming)

• Smiles:

  O=C(NC1=CC=CC=C1)NNC[C@H]2[C@H]([C@H]3O[C@@H]2CC3)C/C=C\CCCC(O)=O

• Molecular Formula:

  C21H29N3O4

• Molecular Weight:

  387.47

• References & Citations:

  [1]Isabella Lawandy, et al. Increased coronary arteriolar contraction to serotonin in juvenile pigs with metabolic syndrome. Mol Cell Biochem. 2019 Nov;461 (1-2) :57-64.|[2]A Hedberg, et al. Characterization of [5, 6-3H] SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets. J Pharmacol Exp Ther. 1988 Jun;245 (3) :786-92.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  98672-91-4