CP-775146

• UNSPSC Description:

  CP-775146 is a selective PPARα agonist that binds strongly to the PPARα ligand. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway[1].

• Target Antigen:

  PPAR

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/cp-775146.html

• Purity:

  98.70

• Solubility:

  DMSO : 42 mg/mL (ultrasonic;warming)

• Smiles:

  CC(OC1=CC=CC([C@H]2CN(C(CC3=CC=C(C(C)C)C=C3)=O)CCC2)=C1)(C)C(O)=O

• Molecular Weight:

  423.54

• References & Citations:

  [1]Shengjie Tang, et al. The Effects of New Selective PPAR α Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism. J Diabetes Res. 2020 May 4;2020:4179852.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  702680-17-9