LY 233053

CAT: 0804-HY-107710Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-107710Size:1 Each
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Description
LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy[1][2].
CAS Number
[125546-04-5]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-233053.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](NCC1)C[C@@H]1CC2=NN=NN2)=O
Molecular Formula
C8H13N5O2
Molecular Weight
211.22
References & Citations
[1]1.K K Borowicz, et al. Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice. Epilepsia. 1996 Jul;37 (7) :618-24. |[2]K P Madden, et al. Efficacy of LY233053, a competitive glutamate antagonist, in experimental central nervous system ischemia. J Neurosurg. 1992 Jan;76 (1) :106-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

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