AVN-322

• UNSPSC Description:

  AVN-322 is an orally active, highly selective 5-HT6Rantagonist for central nervous system disease research[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/avn-322.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=C2N=CC(CN(C)CC3)=C3N2N=C1NC)(C4=CC=CC=C4)=O.Cl

• Molecular Weight:

  393.89

• References & Citations:

  [1]Alexandre V Ivachtchenko, et al. AVN-322 is a Safe Orally Bio-Available Potent and Highly Selective Antagonist of 5-HT6R with Demonstrated Ability to Improve Impaired Memory in Animal Models. Curr Alzheimer Res. 2017;14(3):268-294.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  1194574-68-9