AVN-322

• Description :

  AVN-322 is an orally active, highly selective 5-HT6Rantagonist for central nervous system disease research[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/avn-322.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(C1=C2N=CC(CN(C)CC3)=C3N2N=C1NC)(C4=CC=CC=C4)=O.Cl

• Molecular Formula :

  C17H20ClN5O2S

• Molecular Weight :

  393.89

• References & Citations :

  [1]Alexandre V Ivachtchenko, et al. AVN-322 is a Safe Orally Bio-Available Potent and Highly Selective Antagonist of 5-HT6R with Demonstrated Ability to Improve Impaired Memory in Animal Models. Curr Alzheimer Res. 2017;14 (3) :268-294.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  5-HT6 Receptor

• CAS Number :

  [1194574-68-9]