AVN-322

CAT: 0804-HY-107125Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-107125Size:1 Each
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Description
AVN-322 is an orally active, highly selective 5-HT6Rantagonist for central nervous system disease research[1].
CAS Number
[1194574-68-9]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/avn-322.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=C2N=CC(CN(C)CC3)=C3N2N=C1NC)(C4=CC=CC=C4)=O.Cl
Molecular Formula
C17H20ClN5O2S
Molecular Weight
393.89
References & Citations
[1]Alexandre V Ivachtchenko, et al. AVN-322 is a Safe Orally Bio-Available Potent and Highly Selective Antagonist of 5-HT6R with Demonstrated Ability to Improve Impaired Memory in Animal Models. Curr Alzheimer Res. 2017;14 (3) :268-294.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
5-HT6 Receptor

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