MS-322

• Description :

  MS-322 is an orally active centrally acting muscle relaxant. MS-322 can dose-dependently inhibit spinal reflex potentials, reduce neuronal excitability and muscle afferent discharges, and so on in rats. In addition, MS-322 has relatively weak inhibitory effects on other central nervous system pathways and no effect on the neuromuscular junction[1][2].

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Field of Research :

  Neurological Disease

• Smiles :

  CC[C@H](CN1CCCC1)C(C2=CC(C3=CC=CC=C3)=NO2)=O.Cl

• Molecular Formula :

  C18H23ClN2O2

• Molecular Weight :

  334.84

• References & Citations :

  [1]Otsu T, et al. Muscle relaxant action of MS-322, a new centrally acting muscle relaxant, in rats. Gen Pharmacol. 1998 Mar;30 (3) :393-8.|[2]Otsu T, et al. Pharmacological properties of the new centrally acting muscle relaxant (R) - (+) -3-phenyl-5-[2- (1-pyrrolidinylmethyl) butyryl] isoxazole hydrochloride. Arzneimittel-forschung, 1997, 47 (6) : 706-709.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [144576-50-1]