MK 386

• Description :

  MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].

• Product Name Alternative :

  L-733692

• UNSPSC :

  12352005

• Target :

  5 alpha Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mk-386.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12[C@]3([H])[C@]([C@@H](C)C[C@@]1([H])N(C(CC2)=O)C)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3

• Molecular Formula :

  C28H49NO

• Molecular Weight :

  415.69

• References & Citations :

  [1]Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84 (2) :203-11.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [158493-17-5]