MK 386

• UNSPSC Description:

  MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].

• Target Antigen:

  5 alpha Reductase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mk-386.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@]3([H])[C@]([C@@H](C)C[C@@]1([H])N(C(CC2)=O)C)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3

• Molecular Weight:

  415.69

• References & Citations:

  [1]Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  158493-17-5