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AC-386

CAT: 0804-HY-143463Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143463Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AC-386 is a highly potent c-Met inhibitor with IC50 value of 7.42 nM. AC-386 has antiproliferative activities against certain cancer cell lines. AC-386 can be used for researching anti-cancer resistance[1].
CAS Number
1902910-89-7
UNSPSC
12352005
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-386.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C2=CC=CC=C2)C=C(C)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OCCCN6CCOCC6)=C(OC)C=C45)C(F)=C3
Molecular Formula
C35H34FN5O6
Molecular Weight
639.67
References & Citations
[1]Hu H, Chen F, Dong Y, et al. Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors. Eur J Med Chem. 2020;204:112651.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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