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Asoxime-d4 (dichloride)

CAT: 0804-HY-106901ASSize: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-106901ASSize:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Asoxime-d4 (dichloride) is the deuterium labeled Asoxime dichloride. Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system[1].
Product Name Alternative
HI-6-d4
UNSPSC
12352005
Target
Isotope-Labeled Compounds; nAChR
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Purity
96.0
Solubility
10 mM in DMSO
Smiles
O/N=C/C1=CC=CC=[N+]1COC[N+]2=C([2H])C([2H])=C(C(N)=O)C([2H])=C2[2H].[Cl-].[Cl-]
Molecular Formula
C14H12D4Cl2N4O3
Molecular Weight
363.23
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Pohanka M, et al. HI-6 modulates immunization efficacy in a BALB/c mouse model.Environ Toxicol Pharmacol. 2013 Nov;36 (3) :801-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported