(S) -ABT-102

• Description :

  (S) -ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S) -ABT-102 has analgesic activity[1].

• CAS Number :

  [808756-70-9]

• UNSPSC :

  12352005

• Target :

  TRP Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/s-abt-102.html

• Purity :

  99.64

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1=C2C(NN=C2)=CC=C1)N[C@@H]3C4=CC=C(C(C)(C)C)C=C4CC3

• Molecular Formula :

  C21H24N4O

• Molecular Weight :

  348.44

• References & Citations :

  [1]Gomtsyan A, et al. Identification of (R) -1- (5-tert-butyl-2,3-dihydro-1H-inden-1-yl) -3- (1H-indazol-4-yl) urea (ABT-102) as a potent TRPV1 antagonist for pain management. J Med Chem. 2008 Feb 14;51 (3) :392-5.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported