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Bimosiamose (disodium)

CAT: 0804-HY-106139ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106139ASize:1 Each
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Description
Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose disodium has anti-inflammatory effects[1].
CAS Number
187269-60-9
Product Name Alternative
TBC-1269Z
UNSPSC
12352005
Target
P-selectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bimosiamose-disodium.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]([C@@H](O)[C@H](O)[C@@H]1O)O[C@@H]1OC(C=C2)=C(C3=CC(CC(O[Na])=O)=CC=C3)C=C2CCCCCCC(C=C4)=CC(C5=CC(CC(O[Na])=O)=CC=C5)=C4O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@@H]6O)CO
Molecular Formula
C46H52Na2O16
Molecular Weight
906.88
References & Citations
[1]Palma-Vargas JM, et al. Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion. J Am Coll Surg. 1997 Oct;185 (4) :365-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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