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Bimosiamose

CAT: 0804-HY-106139-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106139-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects[1].
CAS Number
187269-40-5
Product Name Alternative
TBC-1269
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E-Selectin ; L-Selectin; P-selectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Bimosiamose.html
Purity
99.0
Solubility
0.1 M NaOH : 25 mg/mL (ultrasonic; adjust pH to 10 with NaOH) |DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@H]([C@@H](O)[C@H](O)[C@@H]1O)O[C@@H]1OC(C=C2)=C(C3=CC(CC(O)=O)=CC=C3)C=C2CCCCCCC(C=C4)=CC(C5=CC(CC(O)=O)=CC=C5)=C4O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@@H]6O)CO
Molecular Formula
C46H54O16
Molecular Weight
862.91
Precautions
H302, H315, H319, H335
References & Citations
[1]Palma-Vargas JM, et al. Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion. J Am Coll Surg. 1997 Oct;185 (4) :365-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

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A13178-1Bimosiamose 1mg

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