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NP-G2-044

CAT: 0804-HY-125506-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125506-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NP-G2-044 is a potent, orally active fascin inhibitor, with an IC50 of ~2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response[1][2].
CAS Number
1807454-59-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/np-g2-044.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)OC=C1)NC2=NN(CC3=CC=C(C(F)(F)F)C=C3)C4=C2C=CC=C4
Molecular Formula
C21H16F3N3O2
Molecular Weight
399.37
Precautions
H302, H315, H319
References & Citations
[1]Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10 (7) :966-980.|[2]Vincent Chung, et al. Abstract C053: NP-G2-044, a novel fascin inhibitor, blocks tumor metastasis and increases antitumor immune response.|[3]Fascin Inhibitor NP-G2-044.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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