17-PA

• Description :

  17-PA is a selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors[1].

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/17-pa.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12C(C3=CC=CC=C3)=CC[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@H](O)CC[C@]5(C)[C@@]4([H])CC2

• Molecular Formula :

  C25H34O

• Molecular Weight :

  350.54

• References & Citations :

  [1]Mennerick S, et al. Selective antagonism of 5alpha-reduced neurosteroid effects at GABA (A) receptors. Mol Pharmacol. 2004 May;65 (5) :1191-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [694438-95-4]