Products for Research Use Only
RegisterLogin

PA-8

CAT: 0931-T41005-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T41005-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
878437-15-1
Target
PACAP
Related Pathways
GPCR/G Protein
Purity
0.9764
Bioactivity
PA-8 is a small molecule receptor antagonist for PACAP Type I (PAC1) that is selective, effective, and orally active. PA-8 inhibits PacAP-induced CREB phosphorylation at PAC1- receptors, but does not inhibit VPAC1- or vpac2 receptors. PA-8 also inhibited PacAP-induced elevation of cAMP levels in vitro (IC50 = 2 nM) and PacAP-induced aversive response and mechanical atopic pain after intrathecal injection in vivo.
Smiles
COc1cc(ccc1OCC=C)C1CC(=O)Nc2nc(N)[nH]c(=O)c12
Molecular Formula
C17H18N4O4
Molecular Weight
342.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T24585-01PA-9
T33857-01PA Autoinducer
T79530-01SA-PA
T208224-01CL-Pa
TP3013-01PIC1 PA
T41210PA Nic
T68245-01PA-082
T22475-0117-PA
T17311-01(+) -JQ1 PA
T207943-01PA-Nic TFA

Alternative Products

CatalogName
GTR19188708-01PA-8
6657/50PA 8
A88016-40K8-ArmPEG-PA, 40K
A88016-30K8-ArmPEG-PA, 30K
A88016-20K8-ArmPEG-PA, 20K
A88016-10K8-ArmPEG-PA, 10K
HO016016-1K-01PA-PEG-PA, 1K
BLG-P112-01PA (2′,5′) pA
BA5692-5.1PA-9
B7151-1017-PA

Popular Products