SA-PA
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SA-PA
Target :
Ephrin Receptor|||VEGFR|||PROTACs|||PDGFRRelated Pathways :
PROTAC|||Angiogenesis|||Tyrosine Kinase/AdaptorsBioactivity :
SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-?, and EphB4 proteins within U87 cells. In the presence of endogenous copper in tumor tissues, SA-PA undergoes in situ conversion to active PROTAC through a click reaction [1].Molecular Formula :
C40H32ClF3N10O8Molecular Weight :
873.19Shipping Conditions :
Cool packStorage Temperature :
-20°C
