SA-PA

CAT: 0931-T79530-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T79530-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Ephrin Receptor, VEGFR, PROTACs, PDGFR

Related Pathways

PROTAC, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-β, and EphB4 proteins within U87 cells. In the presence of endogenous copper in tumor tissues, SA-PA undergoes in situ conversion to active PROTAC through a click reaction [1].

Molecular Formula

C40H32ClF3N10O8

Molecular Weight

873.19

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
MBS5821192	SA-PA
AI7902	PAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-KRAB-pA Donor Vector
AI8902	PAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-VPR-pA Donor Vector
A2296-90-01	Anisomycin (Flagecidin, Antibiotic SA 3097C1, Antibiotic PA 106, Anhydroscopin A, NSC)
AC8302	PAAVS1-SA-T2A-Neo-CAG-dCas9-VPR-pA Donor Vector
AC7302	PAAVS1-SA-T2A-Neo-CAG-dCas9-KRAB-pA Donor Vector
HO016016-1K-01	PA-PEG-PA, 1K
BLG-P112-01	PA (2′,5′) pA
abx085045-01	SA-PEG-SA
HO013013-4K-01	SA-PEG-SA, 4K

SA-PA

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