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SA-PA

CAT: 0931-T79530-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T79530-01Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ephrin Receptor|||VEGFR|||PROTACs|||PDGFR
Related Pathways
PROTAC|||Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-?, and EphB4 proteins within U87 cells. In the presence of endogenous copper in tumor tissues, SA-PA undergoes in situ conversion to active PROTAC through a click reaction [1].
Molecular Formula
C40H32ClF3N10O8
Molecular Weight
873.19
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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