CNS 5161

• Description :

  CNS-5161 is a novel NMDA ion-channel antagonist that interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.

• CAS Number :

  [160754-76-7]

• UNSPSC :

  12352005

• Target :

  IGluR

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/cns-5161.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N=C(NC1=CC(SC)=CC=C1Cl)N(C)C2=CC=CC(SC)=C2

• Molecular Formula :

  C16H18ClN3S2

• Molecular Weight :

  351.92

• References & Citations :

  [1]Walters MR, et al. Early clinical experience with the novel NMDA receptor antagonist CNS 5161. Br J Clin Pharmacol. 2002 Mar;53 (3) :305-11.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2