CNS-11

• UNSPSC Description:

  CNS-11 is a compoud that disaggregates tau fibrils. CNS-11 can be used for Alzheimer's disease (AD) research[1].

• Target Antigen:

  Tau Protein

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cns-11.html

• Solubility:

  DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C1C2=C(C3=CC=C2)C(C4=CC=CC=C34)=NN1CC(NC(C(C)=CC(C)=C5)=C5C)=O

• Molecular Weight:

  395.45

• References & Citations:

  [1]Paul M Seidler, et al. Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro. Nat Commun. 2022 Sep 16;13(1):5451.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  445218-34-8