SCH 336

• Description:

  SCH 336 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice[1].

• Product Name Alternative:

  SCH-225336

• UNSPSC:

  12352005

• Target:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sch-336.html

• Concentration:

  10mM

• Purity:

  98.63

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CS (N[C@H] (C1=CC=C (C=C1) S (C2=C (C=C (C=C2) OC) S (=O) (C3=CC=C (C=C3) OC) =O) (=O) =O) C) (=O) =O

• Molecular Formula:

  C23H25NO8S3

• Molecular Weight:

  539.64

• References & Citations:

  [1]Lunn CA, et al. A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo. J Pharmacol Exp Ther. 2006 Feb;316 (2) :780-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB2

• CAS Number:

  447459-51-0