LY 235959

• Description:

  LY 235959 is a competitive N-methyl-D-aspartate (NMDA) -receptor antagonist. LY 235959 potentiates the anticonvulsant action of antiepileptics[1].

• Product Name Alternative:

  (-) -LY 235959

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  IGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ly-235959.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC ([C@@H]1C[C@]2 ([H]) [C@@] (CN1) ([H]) CC[C@@H] (C2) CP (O) (O) =O) =O

• Molecular Formula:

  C11H20NO5P

• Molecular Weight:

  277.25

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]K K Borowicz, et al. Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice. Epilepsia. 1996 Jul;37 (7) :618-24.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  137433-06-8