RegisterLogin

C-11

CAT: 804-HY-100861Size: 1 EachDry Ice: NoHazardous: No
1 EachSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
C-11 is a tubulin inhibitor and acts as an ADC cytotoxin, displays cytotoxicity for carcinoma cell lines[1].
CAS Number
[2007965-97-9]
UNSPSC
12352203
Target
ADC Payload; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-11.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)[C@@H](C(C)C)C[C@@H](OC(C)=O)C1=NC(C(N[C@@H](CC2=CC=C(N)C=C2)C[C@H](C)C(O)=O)=O)=CS1)[C@H]([C@@H](C)CC)NC([C@@]3(C)CCCN3C)=O
Molecular Formula
C38H58N6O7S
Molecular Weight
742.97
References & Citations
[1]Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7 (11) :999-1004.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents

Related Products

CatalogName
HY-177286C-Kit-IN-11
HY-147694C-Met-IN-11
HY-155507C-Myc inhibitor 11
HY-P4699(Thr17) -c-Jun (11-23)
HY-15162711β-HSD1-IN-11
HY-112533-0111-Deoxy-11-methylene PGD2
HY-W09805111-Methoxy-11-oxoundecanoic acid
HY-147581BTK-IN-11
HY-122934-0111-Methoxyangonin
HY-145055HBV-IN-11

Alternative Products

CatalogName
MBS3844915-01C-11
T10640-01C-11
MBS5766247C-11
sc-514251C-Fgr (C-11)
216181CCL-11 (Chemokine C-C Motif Ligand 11)
MBS5806324c-Met-IN-11
sc-166214Uricase (C-11)
sc-398905Dysferlin (C-11)
sc-374657Serglycin (C-11)
sc-17787γ Tubulin (C-11)

Popular Products