T-3256336

• Description :

  T-3256336 is a potent and orally active cIAP1 and XIAP inhibitor with IC50s of 1.3, 200 nM, respectively. T-3256336 shows anti-tumor activity[1].

• UNSPSC :

  12352005

• Target :

  IAP

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/t-3256336.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@H]1N(C([C@H](C2CCC(F)(F)CC2)NC([C@@H](NC)C)=O)=O)C[C@](C[C@@H](OCC)C3)([H])N3C1)N[C@@H]4CCOC5=CC=CC=C45

• Molecular Formula :

  C31H45F2N5O5

• Molecular Weight :

  605.72

• References & Citations :

  [1]Hashimoto K, et al. Design and synthesis of potent inhibitor of apoptosis (IAP) proteins antagonists bearing an octahydropyrrolo[1,2-a]pyrazine scaffold as a novel proline mimetic. J Med Chem. 2013 Feb 14;56 (3) :1228-46.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CIAP-1; XIAP

• CAS Number :

  [1266227-69-3]