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Ro 3-1314

CAT: 0804-HY-N8276Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8276Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ro 3-1314 (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. Ro 3-1314 is a linoleic acid metabolism inhibitor. Ro 3-1314 stimulates the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substance of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments[1].
CAS Number
2012-14-8
Product Name Alternative
9a,12a-Octadecadiynoic acid
UNSPSC
12352211
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ro-3-1314.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCCC#CCC#CCCCCC)O
Molecular Formula
C18H28O2
Molecular Weight
276.41
References & Citations
[1]M Hitchcock, et al. Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid. Br J Pharmacol. 1981 Apr;72 (4) :689-95.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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