ATPA

CAT: 0804-HY-101261-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101261-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5 (S741M), GluR5 (S721T), GluR5 (S721T, S741M), GluR5 (S741A), GluR5 (S741L), and GluR5 (S741V), respectively[1].
CAS Number
[140158-50-5]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/atpa.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)C(N)CC1=C(C(C)(C)C)ONC1=O
Molecular Formula
C10H16N2O4
Molecular Weight
228.25
References & Citations
[1]Nielsen MM, et al. The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741. Mol Pharmacol. 2003 Jan;63 (1) :19-25.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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