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ATP (dimagnesium)

CAT: 0804-HY-B2176B-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2176B-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation[1][2].
CAS Number
74804-12-9
Product Name Alternative
Adenosine 5'-triphosphate (dimagnesium)
UNSPSC
12352200
Hazard Statement
H371
Target
Endogenous Metabolite
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/atp-dimagnesium.html
Purity
98.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=P([O-])([O-])OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1O)([O-])=O)([O-])=O.[Mg+2].[Mg+2]
Molecular Formula
C10H12Mg2N5O13P3
Molecular Weight
551.76
Precautions
H371
References & Citations
[1]Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35 (3) :852-8.|[2]M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112 (2) :358-404.|[3]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514.|[4]Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8 (5) : e63759.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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