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RMXL1 rabbit pAb

CAT: 0855-ES13378-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13378-01Size:50 µL
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Background
This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009]
Description
This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009],
UniProt
Q96E39
Swiss Prot
Q96E39
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human RMXL1 AA range: 304-354
Target
RMXL1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus .
Gene ID (Human)
494115

UniProtKB · Q96E39

RNA binding motif protein, X-linked-like-1

RMXL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96E39
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RBMXL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Biological process

mRNA processingmRNA splicing

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Molecular function

RibonucleoproteinRNA-binding

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