Runx1-CBFβ interaction inhibitor 1

• UNSPSC Description:

  Runx1-CBFβ interaction inhibitor 1 is an allosteric inhibitior of Runt domain-CBFb interaction (IC50=3.2 μM)[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/runx1-cbfβ-interaction-inhibitor-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(C=C1)=CC=C1C2=C(CC)SC(N)=N2

• Molecular Weight:

  234.32

• References & Citations:

  [1]Michael J Gorczynski, et al. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chem Biol. 2007 Oct;14(10):1186-97.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  493028-20-9