PSB-1491

• Description :

  PSB-1491 is a selective and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 of 0.386 nM for hMAO-B. PSB-1491 shows >25000-fold selective versus MAO-A[1].

• UNSPSC :

  12352005

• Target :

  Monoamine Oxidase

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/psb-1491.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1=CC=C(C(Cl)=C1)Cl)C2=CC3=C(C=C2)N(N=C3)C

• Molecular Formula :

  C15H11Cl2N3O

• Molecular Weight :

  320.17

• References & Citations :

  [1]Tzvetkov NT, et al. Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57 (15) :6679-703.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MAO-B

• CAS Number :

  [1619884-67-1]